It’s a fact that Weblogic domains are dynamic in nature, especially when SOA components are involved. Out of the box Cloud Control does not update the target list of a Weblogic domain. Ofcourse you can manually trigger a refresh of the Weblogic domain, but it would be much better to automate this procedure.
Automation can be achieved by enabling the ‘refresh domain’ job per domain.
Go to a domain and under the ‘General’ tab, click on the ‘Weblogic Domain Refreshed’ date.
More information in the Discovering New or Modified Domain Members in the Cloud Control Admin Guide.